Trinnpris angis for ikke-patenterte legemidler, hvor det foreligger generisk konkurranse mellom legemidler som Direktoratet for medisinske produkter har vurdert som likeverdige.
Advarsler og forsiktighetsregler Snakk med lege eller apotek før du bruker Modiodal dersom du Har hjerteproblemer eller høyt blodtrykk. Legen din må sjekke dette regelmessig mens du tar Modiodal.
anastrozole will enhance the level or influence of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unidentified.
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Modafinil is both fast-acting and extended-lasting. It can be metabolized while in the liver, and peak plasma concentrations happen within two – 4 several hours, however initial consequences could be felt inside an hour or so.
Monitor INR more often if coadministered with inhibitors of these isoenzymes and change warfarin dose if necessary.
Stone et al (2002) also noted the results of anxiety on modafinil’s stimulation of more info enhanced gross motion in live rats, several of whom were being pretreated with corticosterone or dexamethasone. They noted that anxiety diminished Over-all gross motion, an influence attenuated by corticosterone pre-procedure, and worry also lessened the modafinil induced boost in gross motion.
While modafinil habit is identified as a likelihood, it can be widely thought to own significantly reduce addiction danger than amphetamines[twelve] and it has even been proposed to be a cure for methamphetamine and copyright addictions.
Observe Intently (1)modafinil will increase the amount or effect of citalopram by influencing hepatic enzyme CYP2C19 metabolism. Use Warning/Keep an eye on. Citalopram 20 mg/working day is the maximum recommended dose for patients getting CYP2C19 inhibitors due to the danger of QT prolongation.
Modafinil is known to own fewer or no adverse results than People located in traditional psychostimulants including amphetamine, methylphenidate or copyright. It could be used being an anti-psychotic or anti-fatigue agent.
modafinil will minimize the extent or impact of norgestrel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Reasonable CYP3A4 inducers may well decrease progestin concentration; take into account usage of supplemental barrier techniques
Doses approximately 400 mg/day, offered as one dose, have already been well tolerated, but there is no reliable proof that this dose confers added profit past that on the 200 mg/day dose
Observe Closely (1)enasidenib will increase the level or effect of modafinil by affecting hepatic enzyme CYP2C19 metabolism.
It's not identified regardless of whether modafinil passes into breast milk or if it could harm a nursing baby. Notify your physician In case you are breast-feeding a infant.